The Herpesvirus is the virus that causes the sexually transmitted disease known as herpes. It has become very common worldwide with over 62% of Americans are infected with hsv-1 herpes. Every one in four women have it compared to every one in eight men. There are two main types of herpesvirus. Hsv-1 which is the mouth herpes, it also causes half of all genital herpes, and then hsv-2 herpes is considered the genital herpes. There are many different ways to get hsv-1 herpes, unlike hsv-2 herpes were the only way you can get it is by doing sexual activities. There are ways of preventing herpes, but there is still no actual cure for it.
Electron microscopes have been studying the simplex virus 1 DNA. They found that it consists of two unequal regions. They are both bounded by inverted redundant sequences. One region is named L and in consists of 70% of the contour length of the DNA. L also has two terminal regions and their names are a1b and b’a’1. The a1b region separates the left terminal from its inverted repeat b’a’1. Each has 6% DNA.
The second region is named S and it consists of 9.4% of the DNA. This one separates the right terminal region CAS from its repeat a’sc’. Each is 4.3 % DNA. Since the two region terminals they differ in topology. CAS is guanine plus cytosine rich witch the others are guanine plus cytosine rich.
Modes of Infection
Herpes is very common worldwide. The Hsv-1is the main cause to infections in the mouth, lips, and cause up to half of all genital herpes. Some examples of lip herpes are cold sores and fever blisters. Some ways herpes are spread are through kissing, sharing drinks, drinking utensils, saliva, personal items such as (a razor), and oral sex from someone who has Hsv-1 can cause you to contact the virus. Hsv-1 is extremely common, about 90% of American adults have been exposed to the virus. Hsv-1 infections can be sexually transmitted. Some signs and symptoms of Hsv-1 are small, painful blisters filled with fluid around the lips or edge of the mouth. Tingling or burning around the mouth or nose, often a few days before the blister appears. When you have a fever, sore throat, and swollen lymph nodes in the neck. Some preventive care for Hsv-1 is reduce stress, don’t kiss people with visible cold sores, wash hands frequently, and use sunscreen. If you already have Hsv-1 be careful when touching your eyes and genitals, don’t perform oral sex on your partner.
Hsv-2 is the main cause of genital herpes. The only way to get hsv-2 is by sexual activity. Some people that are infected with herpes don’t know they have it and that’s because they don’t have any signs. There is still no cure for herpes. Once you have herpes once it’s most likely to come back. But some people are lucky and they will have an outbreak of herpes and then it will never come back. People who have hsv-2 herpes are embarrassed by it. There are ways for people to prevent the spreading of hsv-2, and they are still able to have a normal sex life. It is very life threatening for infants, people with a weakened immune system, and people with infections in the eyes. Some hsv-2 symptoms and signs are tingling sensation in the genital, buttocks, and thighs, small red blisters or open sores on genitals or inner thighs, in women, often occur inside the vagina, may be painful or not, in women, vaginal dis charge, fever, muscle aches, headache, painful urination, and swollen lymph glands in the groin. Some hsv-2 preventive care is avoid having sex with your partner if one of you has an outbreak, avoid touching the sores, have your partner use a condom that has latex in it, even if the sores are not visible, limit sex partner numbers.
Herpes began as early as ancient Greek times. It was mentioned in ancient Greek writings. The word herpes is even a Greek word which means to creep or crawl. The Greeks even described the way that the skin lesions spread.
In Roman times, the emperor Tiberius tried to stop an outbreak of herpes that were in the mouth. He prohibited kissing at public events and ceremonies. In the play Romeo and Juliet written by Shakespeare, he even talks about blister plagues. People believe those plagues to be a type of herpes. There are many medical journals from the 1700’s to the 1800’s that talk about this disease. Some people said it may have started from a bug bite.
- Wadsworth, R J Jacob, and B Roizman. Anatomy of herpes simplex virus DNA. II. Size, composition, and arrangement of inverted terminal repetitions. PMC. Web. Jun 1975.
- Herpes simplex virus University of Maryland Medical center. Web.
- Miller, Sheldon. What is The History of Herpes and How is it Spread? ezine articles. Web. Submitted On June 03, 2007.